Multiplatform Molecular Profiling

Multiplatform molecular profiling identifies potentially targetable biomarkers in malignant phyllodes tumors of the breast.

Malignant phyllodes tumor is a rare breast malignancy with sarcomatous overgrowth and with limited effective treatment options for recurrent and metastatic cases. Recent clinical trials indicated a potential for anti-angiogenic, anti-EGFR and immunotherapeutic approaches for patients with sarcomas, which led us to investigate these and other targetable pathways in malignant phyllodes tumor of t...

Gena: Multiplatform Generic Agents

Mobile agents in the Internet environment bring new constraints. In particular, various agent platforms will coexist on the Net. Our generic agent model “GenA” allows agents to run on and move between different agent platforms by using an interface called “GenAi.” Programming these GenA agents is independent of the underlying agent platforms. An implementation of this agent model has been perfo...

GenA : Multiplatform Generic Agents

Multiplatform Universal Visualization Architecture

Information visualization techniques are invaluable tools in numerous applications such as those involving large databases and document collections. Ubiquitous usage of such techniques can provide universal access to complex information. The main goal of our work is to provide such universal visual access to information through the proposed Multiplatform Universal Visualization Architecture (MU...

Transcriptomes of the B and T lineages compared by multiplatform microarray profiling.

T and B lymphocytes are developmentally and functionally related cells of the immune system, representing the two major branches of adaptive immunity. Although originating from a common precursor, they play very different roles: T cells contribute to and drive cell-mediated immunity, whereas B cells secrete Abs. Because of their functional importance and well-characterized differentiation pathw...